The combination of CNS acting muscle relaxants, non-steroidal medicine medication and paracetamol are normally prescribed in the management of mechanical low backache. To compare the effectiveness of combination drugs chlorzoxazone, ibuprofen and paracetamol versus thiocolchicoside, aceclofenac and paracetamol in subjects having low backache. A total of one hundred patients between ages vary from eighteen and sixty years having acute lower backache of ≤7 days length were categorized as groups. Group A type was prescribed with thiocolchicoside, paracetamol and aceclofenac whereas Group B type was prescribed with chlorzoxazone, aceclofenac and paracetamol orally doubly daily for seven days. The pain assessment, calculated by VAS and ODI. Readings were recorded on day one (baseline) and day seven. A significant pain reduction occurred on day seven in two groups. It was observed statistically that relief in pain varied in 2 groups, however clinically Group-B subjects shown better efficacy compared to Group-A. These findings confirm that chlorzoxazone, paracetamol, ibuprofen is a preferable combination for patients having low backache.
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